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A Clinical Triad to Diagnose Paraneoplastic Retinopathy
Ann Neurol 28:162-167, Jacobson,D.M.,et al, 1990
See this aricle in Pubmed

Article Abstract
Two elderly men developed photosensitivity and light-induced glare, transient visual symptoms,and progressive visual loss several months before small cell carcinoma of the lung was discovered.Both patients had impaired visual acuity and color vision,ring scotomas,and attenuated retinal arteriole caliber.Electroretinography demonstrated abnormal cone and rod-mediated responses.Antiretinal antibodies were identified in their serum.Their visual sensory function improved following therapy with immunosuppressive agents.The triad of photosensitivity,ring scotomatous visual field loss,and attenuated retinal arteriole caliber should alert one to a paraneoplastic disorder affecting the retina.
 
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antiretinal antibodies
autoantibodies
CAR syndrome
carcinoma of lung
color vision
color vision,impaired
electroretinograph
fundus,abnormality of
glare,light-induced
immunosuppressive agents
photophobia
photosensitivity,eye
remote effect of cancer on the nervous system
retinal arteriole attenuation
retinal degeneration
retinal lesion
retinopathy
scotoma
steroid
steroid therapy,CNS treatment and complications with
visual acuity
visual acuity,decreased
visual loss
visual loss,slow

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